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Materials Science and Engineering, University of Michigan

  MSE / Research / Projects / Highly Sensitive, Selective, Self-Signal Amplifying Molecular DNA Sensors

Highly Sensitive, Selective, Self-Signal Amplifying Molecular DNA Sensors

Collaborators: Erdogan Gulari
Materials: Nanomaterials Organic
Application: Nanotechnology Energy Biomedical
Technique: Synthesis Processing Characterization

Low cost, reliable detection of bio-threat agents remains a significant challenge especially given the diversity of the potential agents which can be used for this purpose. The most reliable way of identifying the identity of any virus or microbe is through its genetic code. The US Post Office for example has now in place a PCR-based detection system for anthrax spores. However, the system is specialized to anthrax alone and does one check approximately every hour at a cost of several hundred dollars. It is our goal in this project to develop the necessary tools for detecting up to several thousand agents simultaneously in a short time with very low false positive rate and using very small amount samples.


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